Projects & Theses

Below you find a collection of BSc and MSc projects and theses that can be carried out within the MaP community.

ETH Zurich uses SiROP to publish and search scientific projects. For more information visit sirop.org.

Development of Wireless Ion Sensing Platforms using Metamaterials and Soft Biointerfaces

This project explores the design and realization of a flexible, wireless ion-sensing patch by integrating resonant metamaterial structures with bio-interfacing soft materials. The system is intended for noninvasive detection of physiologically relevant ions from skin-interfaced fluids using passive sensing mechanisms

Keywords

flexible electronics, metamaterials, wireless biosensors, resonant sensors, skin-compatible interfaces

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Published since: 2025-12-23 , Earliest start: 2026-01-15 , Latest end: 2026-10-29

Organization Biomedical and Mobile Health Technology Lab

Hosts Zada Muhammad

Topics Engineering and Technology

Multi agent motion planning with (learned) behaviours

We want to incorporate learned skills and preprogrammed controllers into multi agent planning.

Keywords

multi agent motion planning

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Master Thesis

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Published since: 2025-12-22 , Earliest start: 2026-01-01

Organization Computational robotics laboratory (Prof. Stelian Coros)

Hosts Hartmann Valentin

Topics Information, Computing and Communication Sciences

Benchmarking robotic multi agent reinforcement learning

Good task allocation is crucial for efficiency in multi robot systems. We want to benchmark algorithms and approaches for this problem in this thesis.

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Semester Project , Master Thesis

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Published since: 2025-12-22

Organization Computational robotics laboratory (Prof. Stelian Coros)

Hosts Hartmann Valentin

Topics Information, Computing and Communication Sciences , Engineering and Technology

Learning precise cube reorientation from human priors

Dexterous multi finger tasks are still hard. We want to evaluate reinforcement learning with human priors for the cube reorientation task in this work.

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Master Thesis

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Published since: 2025-12-22

Organization Computational robotics laboratory (Prof. Stelian Coros)

Hosts Hartmann Valentin

Topics Information, Computing and Communication Sciences , Engineering and Technology

In vitro liver models for high-throughput screening of pro-regenerative treatments to recondition human organs for transplantation

Many organ grafts are not suitable for transplantation due to excessive ischemic injury. In an effort to save these discarded grafts, ex vivo perfusion systems have been developed to extend the time window for organ repair. The liver, in particular, has a remarkable regenerative capacity and its ex vivo perfusion provides a unique opportunity to trigger regeneration pathways. Thus far, advanced perfusion technologies have enabled the preservation of the human liver outside of the body for up to two weeks using normothermic machine perfusion. Until now, this liver perfusion machine has only been employed to treat bacterial infections, determine tumour malignancy and assess liver function, yet how to stimulate growth and repair of liver grafts ex vivo remains unexplored. In order to effectively develop regeneration strategies, in vitro liver models are necessary since ex vivo human liver experiments are low-throughput, confounded by patient to patient variability and costly. Liver tissue slices, which are directly obtained from native liver tissue, preserve the intact hepatocellular architecture and microenvironment of the liver unlike 2D cell culture and organoid models. Thus, we aim to use liver tissue slices as a screening platform to identify pro-regenerative biomolecules and drugs. In addition, we will explore mRNA lipid nanoparticles to improve the delivery and therapeutic effect of candidate biomolecules and drugs for ex vivo liver perfusion.

Keywords

in vitro liver models, regeneration, drug screening, cell culture, molecular biology, biomedical engineering, high-throughput, mRNA LNP, drug delivery systems, in vitro model, liver, translation

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Internship , Master Thesis

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Published since: 2025-12-21 , Earliest start: 2026-01-11 , Latest end: 2026-12-31

Organization Macromolecular Engineering Laboratory

Hosts Cunningham Leslie

Topics Engineering and Technology , Biology

Optical Glucose Sensor for a Perfusion System

Organ perfusion is a method by which blood and other fluids are oxygenated and pumped through organs including livers, kidneys, lungs and hearts in order to provide the organ with oxygen and nutrients. Various organ perfusion technologies are already in clinical use to improve organ preservation or even treat organs prior to transplantation. Furthermore, ex-vivo perfusion offers the unique opportunity to study whole organs as an isolated system. Robust organ perfusion systems require close control of perfusate parameters such as pH, oxygenation, flow, pressure, glucose concentration etc. While some parameters such as flow and pressure can be monitored with reusable sensors, others like pH, oxygenation and glucose require disposable sensors that are expensive and can only be used once. Because of high costs of these sensors, most perfusion systems are either too simplified and don’t account for these parameters or are so expensive that only very few laboratories conduct research with them. Therefore, development of cheap sensors, that can be easily produced, is important to advance research in organ perfusion.

Keywords

Optics, Glucose, Perfusion, Human

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Master Thesis , ETH Zurich (ETHZ)

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Published since: 2025-12-19 , Earliest start: 2026-02-01 , Latest end: 2026-11-01

Organization Macromolecular Engineering Laboratory

Hosts Binz Jonas

Topics Engineering and Technology

Braided Helical Capacitive Strain Sensor

The aim of the project is to develop a simple fabrication method for braided capacitive strain sensors. This involves wet-spinning stretchable, insulated and conductive fibers, and subsequently braiding them with conductive thread to obtain a capacitive strain sensor. This new production method is expected to streamline the manufacture of highly sensitive strain sensors.

Keywords

wearable, e-textiles, braiding, wet-spinning, capacitive strain sensors

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Master Thesis

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Published since: 2025-12-19 , Earliest start: 2026-01-12 , Latest end: 2026-12-31

Organization Biomedical and Mobile Health Technology Lab

Hosts Kateb Pierre

Topics Engineering and Technology

Subharmonic emissions from acoustically-coupled microbubble clouds

In the medical context, coated microbubbles have the potential to measure the cardiac pressure noninvasively by means of subharmonic emissions. In this study, we aim to study the influence of acoustic coupling between neighboring microbubbles in the amplitude of the subharmonic emissions.

Keywords

Microbubble dynamics, numerical, subharmonic, pressure estimation.

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Semester Project , Bachelor Thesis , ETH Zurich (ETHZ)

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Published since: 2025-12-19 , Earliest start: 2026-01-05

Applications limited to ETH Zurich

Organization Group Supponen

Hosts Collado Gonzalo

Topics Engineering and Technology , Physics

Ultrasonic Plasma Atomization of Recycled Aluminum–Carbide Composite Feedstock for Additive Manufacturing

Pre-fabricated aluminum–carbide composite rods produced from recycled aluminum powder are used as feedstock for Ultrasonic Plasma Atomization (UPA). The rods are melted and atomized by the combined action of a plasma jet and ultrasonic excitation, producing rapidly solidified composite powder particles. The resulting powders are collected and characterized in terms of particle size distribution, morphology, and internal microstructure, with particular focus on reinforcement retention and homogeneity. In a secondary step, selected composite wires are further reduced in diameter by rolling to evaluate formability and suitability for wire-based additive manufacturing processes.

Keywords

Ultrasonic Plasma Atomization Aluminum Matrix Composites Additive Manufacturing Powder characterization

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Bachelor Thesis

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Published since: 2025-12-19 , Earliest start: 2026-02-01 , Latest end: 2026-05-31

Organization Advanced Manufacturing Laboratory

Hosts Fichter Pauline

Topics Engineering and Technology

Numerical investigations of the nonlinear coupling between the shape modes and volumetric oscillations of microbubbles

Microbubble dynamics are rich and complex. When they are excited with an ultrasound wave, these can undergo spherical and non-spherical oscillations. Experimental results suggest that non-spherical shape modes can couple with the spherical oscillation, leading to some unexpected behaviors. In this project we aim to numerically investigate this phenomenon.

Keywords

Microbubble, dynamics, partial differential equations, numerical

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Semester Project , Bachelor Thesis , Master Thesis , ETH Zurich (ETHZ)

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Published since: 2025-12-19 , Earliest start: 2026-01-05

Applications limited to ETH Zurich

Organization Group Supponen

Hosts Collado Gonzalo

Topics Mathematical Sciences , Engineering and Technology , Physics

Assessing the acute and long-term effects of an app intervention on stress using multimodal wearable data

This project investigates changes in stress levels over the course of a longitudinal app-based intervention, as well as acute physiological responses during app use. A wide range of physiological signals were recorded using wearable devices to comprehensively capture autonomic regulation and correlates of stress.

Keywords

electrocardiography (ECG), electrodermal activity (EDA), photoplethysmography (PPG), respiration, electroencephalography (EEG), smart-watch, wearable devices, machine learning, artificial intelligence, signal processing, data analysis, stress, sleep

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Published since: 2025-12-18 , Earliest start: 2026-01-05 , Latest end: 2026-12-31

Organization Biomedical and Mobile Health Technology Lab

Hosts Luster Alexandre

Topics Information, Computing and Communication Sciences , Engineering and Technology

Open-Source Physical AI for Bimanual Contact-Rich Tasks

The aim of this work is to advance fundamental problems in physical AI, including coordinated bimanual control, representation and exploitation of contact interactions, and sim-to-real transfer. The project involves commissioning two OpenArm robotic arms in a leader–follower teleoperation setup, followed by the development and evaluation of learning-based bimanual control strategies. You will collect and generate manipulation data both through teleoperation and in simulated environments, and train coordinated bimanual control policies for contact-rich tasks using NVIDIA Isaac Lab or related frameworks. The project provides substantial freedom, allowing you to explore ideas that align with your personal interests. Foreseen applications include dexterous manipulation in manufacturing, household environments, or assistive robotics. Contributions to the OpenArm project are strongly encouraged.

Keywords

AI, Machine Learning, Robotics

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Internship , Bachelor Thesis , Master Thesis

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Published since: 2025-12-18 , Earliest start: 2026-01-01 , Latest end: 2026-12-31

Organization pd|z Product Development Group Zurich

Hosts Gimeno Lucas

Topics Engineering and Technology

Imitation learning in Electronics Disassembly

Disassemblage of Batteries is a challenging task with high variability, due to changing part geometries, corrosion, dirt, etc. The goal of this Thesis is to demonstrate an imitation-learning based disassembly of a PC Mainboard by removing all the cabling with a robot-arm.

Keywords

imitation learning, AI, Machine Learning, Control, Robotics, industry

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Published since: 2025-12-18 , Earliest start: 2025-12-31 , Latest end: 2026-09-30

Organization pd|z Product Development Group Zurich

Hosts Gimeno Lucas

Topics Engineering and Technology

Engineering of a Smart Consumable-Check Module (prototype, hardware, firmware) for innovative diagnostic devices

DiaxxoCare is a Point-of-Care PCR platform designed for professional use in decentralized and resource-limited settings, where robustness against user mistakes is essential. This project develops an implementation-ready checkpoint system that detects missing or incorrectly placed consumables and unsafe device states (e.g., door/lid not closed), guides the user to recover via the UI, and blocks or pauses the workflow when required conditions are not met. The work includes sensor/actuator selection, firmware/software logic, prototype integration, and validation testing to enable fast deployment on commercial devices.

Keywords

Point-of-Care diagnostics; consumable detection; sensors; actuators; embedded systems; firmware; interlocks; human factors; prototyping; verification & validation; medical/veterinary devices; diaxxoCare

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Semester Project , Course Project , Internship , Bachelor Thesis , Master Thesis

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Published since: 2025-12-17 , Earliest start: 2026-01-01 , Latest end: 2026-08-31

Organization Functional Materials Laboratory

Hosts Gregorini Michele

Topics Engineering and Technology

Operator Learning for Plasticity

We aim to explore general strategies that can be applied to operator learning frameworks and are specific to history-dependent material behaviors.

Keywords

Scientific Machine Learning; SciML; Plasticity; Solid Mechanics; Operator Learning; Artificial Intelligence for Science; Machine Learning;

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Semester Project , Master Thesis

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Published since: 2025-12-16 , Earliest start: 2026-03-01

Organization Computational Mechanics Group

Hosts Mousavi Sepehr

Topics Information, Computing and Communication Sciences , Engineering and Technology

Novel wearable kirigami structures for force-based motion monitoring

The aim of this project is to develop auxetic kirigami-inspired molded sensors using flexible substrates, starting with mechanical simulations (FEA) to guide the design. The resulting technology will enable advancements in wearable electronics for precise force-based sensing applications.

Keywords

finite element analysis, wearable, flexible electronics, kirigami, 3D printing, sensor design, wireless communication

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Published since: 2025-12-16 , Earliest start: 2026-01-12 , Latest end: 2026-12-31

Organization Biomedical and Mobile Health Technology Lab

Hosts Kateb Pierre

Topics Engineering and Technology

Agentic AI for Creating Large Solid Mechanics Datasets

We aim to design and create a framework that uses language model agents to create large physics datasets with minimum human intervention or supervision.

Keywords

Solid Mechanics; Material Modeling; Scientific Machine Learning; SciML; Finite element method; Large language models; LLMs; Agentic AI; NLP

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Master Thesis

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Published since: 2025-12-16 , Earliest start: 2026-02-16

Organization Computational Mechanics Group

Hosts Mousavi Sepehr , Massoudi Soheyl

Topics Mathematical Sciences , Information, Computing and Communication Sciences , Engineering and Technology

Temperature-Dependent Mechanic of Highly Entangled Polyacrylamide-Based Hydrogels

This project explores the temperature-dependent mechanical behavior of highly entangled poly(acrylamide-co-oligoethylene glycol acrylate) hydrogels, with the aim of linking experimental stress–strain data to predictive mathematical models for viscoelastic materials. These polymer networks are characterized by high monomer concentrations, low initiator content, and strong topological entanglements, making them an excellent experimental platform for testing modern theories of polymer dynamics. The student will systematically study how mechanical properties such as stiffness, hysteresis, stress relaxation, and nonlinearity evolve with temperature and deformation rate. Mechanical testing will be performed over a controlled temperature range to generate high-quality stress–strain data under compression and, where relevant, cyclic or rate-dependent loading. A central goal is to assess whether existing molecularly informed viscoelastic models can accurately capture the observed behavior, particularly in regimes where entanglements dominate the mechanical response. The project is carried out in close collaboration with a second research group specializing in theoretical and mathematical modeling of soft matter. This provides a rare opportunity to work at the interface between experiment and theory: experimental observations will directly inform model validation, refinement, and parameter selection. The broader motivation is to improve the predictive power of constitutive models for soft, polymer-based materials, which are widely used in applications ranging from adhesives to damping and load-bearing soft solids. This project is well suited for a student who is interested in polymer physics, rheology, or soft-matter mechanics, and who enjoys quantitative thinking. Independence, curiosity, and a willingness to engage with both experiments and theory are essential, as the project offers significant freedom to shape the experimental strategy and contribute original insights.

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Semester Project , Course Project , Internship , Bachelor Thesis , Master Thesis , ETH Zurich (ETHZ)

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Published since: 2025-12-15 , Earliest start: 2026-02-16

Organization Macromolecular Engineering Laboratory

Hosts Mommer Stefan

Topics Engineering and Technology , Chemistry

Inline Quality Control with image analysis & AI

diaxxo, a start-up from ETH Zürich, is revolutionizing molecular diagnostics with a cutting-edge Point-of-Care PCR device. Their innovative technology facilitates rapid, accurate diagnostic testing across human, veterinary, and food applications, especially in developing countries. The PCR process amplifies DNA sequences to identify pathogens accurately. Key to diaxxo's system are specialized aluminum cartridges containing pre-loaded, dried reagents, essential for precise diagnostics. However, current manufacturing challenges in reagent loading and drying affect cartridge quality. The project aims to develop a Quality Control station using advanced imaging and AI to ensure accurate reagent placement and drying, enhancing diagnostic reliability and effectiveness.

Keywords

Image Analysis, AI Technology, High-Resolution Imaging, Visual Data, Quality Control (QC), Automated Decision Making, Defect Detection, Machine Learning, pattern Recognition, Real-Time Analysis

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Semester Project , Bachelor Thesis , Master Thesis

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Published since: 2025-12-13 , Earliest start: 2024-07-21 , Latest end: 2025-06-30

Organization Functional Materials Laboratory

Hosts Gregorini Michele

Topics Information, Computing and Communication Sciences , Engineering and Technology

Data-driven analysis of railway track condition using real-world and simulated GPR measurements

Ground Penetrating Radar (GPR) is an increasingly important tool for assessing the condition of railway infrastructure, particularly with respect to ballast fouling, contamination, and moisture presence, key indicators of track health and long-term performance. In collaboration with SBB and Terra Vermessungen AG, this master thesis investigates how real-world and simulated GPR data can be used to develop robust, data-driven methods for railway track condition assessment. The student will work with extensive field measurements, apply advanced signal processing and statistical/time-series analysis, and explore machine learning approaches to extract meaningful condition indicators from GPR responses. The work will support ongoing research efforts to better understand subsurface behaviour, enhance interpretation of GPR signals, and contribute to the planning and execution of future measurement campaigns on operational railway lines.

Keywords

Ground Penetrating Radar, railway track condition, ballast fouling, moisture detection, machine learning, signal processing

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Published since: 2025-12-12

Organization Structural Mechanics (Prof. Chatzi)

Hosts Arcieri Giacomo

Topics Engineering and Technology

Development of a CO2 Absorption Reactor

Reducing global warming to a minimum requires the deployment of carbon dioxide removal (CDR) technologies to remove CO2 from the atmosphere and compensate for emissions that cannot be completely eliminated. Direct air capture (DAC) with CO2 storage offers a scalable and permanent CDR method. However, DAC is still in its early stages of development. Additionally, high costs, driven in part by significant energy demands, have slowed its widespread adoption. Accelerating research into alternative, energy-efficient approaches is critical to DAC overcoming these barriers and enabling large-scale deployment.

Keywords

CO2, Absorption, Technology, Engineering

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Master Thesis

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Published since: 2025-12-12 , Earliest start: 2026-02-01 , Latest end: 2026-09-30

Organization Laboratory for Electrochemical Energy Systems

Hosts Jauer Marius

Topics Engineering and Technology

Model Compression using the Information Bottleneck Principle for Medical AI and wearable devices

This project investigates the use of the Information Bottleneck (IB) theory as a framework for deep neural network compression, aiming to enhance the deployment of medical AI systems in computationally constrained environments. By quantifying and optimizing the trade-off between information preservation and redundancy, this project explores how IB-based compression can maintain model accuracy while significantly reducing computational load — enabling efficient and scalable medical image segmentation and classification in healthcare applications.

Keywords

machine learning, artificial intelligence, medical AI, information bottleneck, information theory, theoretical machine learning, model compression, deep learning, information theory, U-Net, Vision Transformer (ViT), wearable devices

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Master Thesis

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Published since: 2025-12-12 , Earliest start: 2026-01-01 , Latest end: 2026-10-01

Organization Biomedical and Mobile Health Technology Lab

Hosts Otesteanu Corin, Dr

Topics Information, Computing and Communication Sciences , Engineering and Technology

Let the cells dance!

Dermal Fibroblasts are resident cells in the thickest layer of the skin. They are thought to be sparsely spread out, happily hanging out in their neighborhood. In vitro, we simplify the physiological situation by culturing the cells on 2D substrates to enable us to study them under distinct stimuli. One of which is the stiffness of the matrix that the cells attach to (mimicking for example stiff extracellular matrix of wounded skin vs. soft ECM in healthy skin). Once plated on the substrates, the cells spread and thereby test the substrate stiffness by forming focal adhesions and pulling by contraction, which we can visualize by microscopy imaging after several hours. Dermal Fibroblasts are resident cells in the thickest layer of the skin. They are thought to be sparsely spread out, happily hanging out in their neighborhood. In vitro, we simplify the physiological situation by culturing the cells on 2D substrates to enable us to study them under distinct stimuli. One of which is the stiffness of the matrix that the cells attach to (mimicking for example stiff extracellular matrix of wounded skin vs. soft ECM in healthy skin). Once plated on the substrates, the cells spread and thereby test the substrate stiffness by forming focal adhesions and pulling by contraction, which we can visualize by microscopy imaging after several hours.

Keywords

Mechanobiology, Cell Culture, Live Cell Imaging Expereriments, Image Analysis, Coding

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Semester Project , Internship , Lab Practice , Bachelor Thesis , Master Thesis

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Published since: 2025-12-12 , Earliest start: 2026-01-05 , Latest end: 2026-07-31

Organization Experimental Continuum Mechanics

Hosts Kromer Daniela

Topics Medical and Health Sciences , Engineering and Technology , Biology

Propagation-Based Phase-Contrast Imaging with Cold Neutrons: Towards Tomographic Imaging of Weakly Absorbing Metallic Objects

Neutron imaging provides unique opportunity for studying technologically and biologically relevant materials as a complementary modality to other techniques. The increased interest in neutron imaging relies on their strong penetration into metallic materials, their sensitivity to light elements, and the possibility of manipulating contrast via isotope substitution. Among the imaging approaches, propagation based phase-contrast imaging recently showed a promising extension to conventional absorption transmission imaging. This method, well established with synchrotron X-ray radiation, relies on a (partially) coherent beam and carefully controlled experimental conditions to convert phase variations of the incoming wavefront into quantitative measurements. Note that this opportunity is for the Institut Laue-Langevin in Grenoble, France.

Keywords

phase-contrast imaging; synchrotron radiation; imaging techniques

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Published since: 2025-12-12 , Earliest start: 2026-01-01 , Latest end: 2026-12-31

Organization Group Supponen

Hosts Brewer Cameron

Topics Engineering and Technology

Studying the Stretch Signature of Skin with a Novel Multiplexed Imaging Approach

The skin that wraps our body is constantly subjected to stretch by body movements. To study the stretch signature of the skin, we tested murine stretched skin samples with microindentation and multiplexed imaging. Imaging mass cytometry is a powerful imaging technique where up to 40 markers can be visualized simultaneously. For the first time, this approach allows us to see the microstructure of the skin and with this, study the effects of stretch. In this project we will identify and quantify structural skin properties that are affected by skin stretch. Semi-automated image analysis tools will then be implemented to quantify the skin microstructure under different stretch conditions. These findings we greatly enhance our knowledge of skin, which is needed to optimize treatments like skin expanders.

Keywords

Skin Biomechanics, Imaging Mass Cytometry (IMC), Image Analysis

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Published since: 2025-12-12 , Earliest start: 2025-12-15 , Latest end: 2026-04-30

Organization Experimental Continuum Mechanics

Hosts Kromer Daniela

Topics Medical and Health Sciences , Engineering and Technology , Biology

Implementation of a Quality Management System in a diagnostic startup

The intern/student will support the development and refinement of a practical Quality Management System (QMS) for point-of-care PCR devices and cartridges. The focus is on product and process risk analysis, definition of critical quality control points, and implementation of robust documentation, traceability, and non-conformance management to ensure reliable, high-quality diagnostic products in an industrial start-up environment.

Keywords

Quality Management System, Quality Control, Risk Management, PCR Devices, Cartridges, SOPs, Traceability, Non-Conformance, Diagnostics, Manufacturing

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Semester Project , Internship , Bachelor Thesis , Master Thesis

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Published since: 2025-12-11 , Earliest start: 2026-01-01 , Latest end: 2026-09-01

Organization Functional Materials Laboratory

Hosts Gregorini Michele

Topics Engineering and Technology , Commerce, Management, Tourism and Services , Chemistry

Master Thesis in Learning and Control

We offer a variety of Master Thesis in the topics of Robotics, Learning and Control. Topics include: - imitation learning for cable disassembly - RL-based refinement of imitation learning policies - safe & stable RL and safety filters - encoding high level task primitives with learning policies - 3D and semantic perception of dynamic environments

Keywords

Robotics, Control, Imitation Learning, Reinforcement Learning, Perception, Computer Vision

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Master Thesis

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Published since: 2025-12-11 , Earliest start: 2025-12-31 , Latest end: 2026-09-01

Organization pd|z Product Development Group Zurich

Hosts Gimeno Lucas

Topics Information, Computing and Communication Sciences , Engineering and Technology

Designing a Parametric Software Toolchain for Self-Driving FDM 3D-Printing Laboratories

Self-driving laboratories have shown impressive capabilities in fields such as pharmacy, biology, chemistry, and increasingly in materials discovery, where automated systems execute thousands of experiments with minimal human intervention. Central to these systems is an autonomous design–make–test cycle, in which software and machines interact seamlessly—from parameter selection to fabrication, robotic sample handling, testing, and again parameter optimization. This thesis aims to develop a headless software toolchain that feeds structured and semantic input parameters (high-level geometric parameters) into corresponding parametric CAD models, exports them, configures an automated slicer from the command line, starts print jobs on a real FDM machine, collects test results from a separate testing system, and finally feeds all results into an optimization or decision model that adjusts the input parameters for the next iteration.

Keywords

Design automation, additive manufacturing, 3D-printing, FDM, Slicer, self-driving laboratory (SDL), Prusa XL, FreeCAD, Grasshopper, Closed-loop optimization

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Semester Project , Bachelor Thesis , Master Thesis , ETH Zurich (ETHZ)

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Published since: 2025-12-11 , Earliest start: 2026-02-01 , Latest end: 2026-06-30

Organization pd|z Product Development Group Zurich

Hosts Stein Tom

Topics Engineering and Technology

Multimodal Deep Learning for Gaze-Driven Step Recognition in Orthopedic Training

This project investigates how combining egocentric video with eye-tracking data can improve automated step segmentation in a simulated orthopedic procedure. Using pretrained visual feature extractors and temporal models such as TCNs or Transformers, we aim to predict fine-grained surgical actions and evaluate the added value of gaze information. The goal is to enhance workflow understanding, interpretability, and objective feedback in surgical training.

Keywords

Eye-tracking, Egocentric video, Step segmentation, Orthopedics, Machine Learning, Transformers, Convolutional Neural Networks

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Published since: 2025-12-11 , Earliest start: 2026-01-05 , Latest end: 2026-12-31

Organization pd|z Product Development Group Zurich

Hosts Hogenkamp Maarten

Topics Medical and Health Sciences , Information, Computing and Communication Sciences , Engineering and Technology

Informed Exploration in Reinforcement Learning via Sampling-Based Planning

Robust locomotion across diverse terrains remains one of the most challenging and exciting problems in legged robotics. While deep reinforcement learning (RL) has enabled impressive quadrupedal behaviors, generalization to unseen or complex terrains often suffers from low sample efficiency. To address this, researchers typically rely on labor-intensive curriculum design, where training terrains are manually structured to progress from easy to difficult, while trying to avoid catastrophic forgetting. These staged curricula allow the RL agent to master simple environments before tackling more complex ones. However, even with such manually designed curricula, RL training can take several days. This is partly because the agent does not retain knowledge about where it has succeeded or failed, nor does it use this experience to inform future exploration. This project aims to develop an automated approach to guide the RL exploration by leveraging sampling-based planning techniques. We formulate the training process as a graph expansion problem, wherein the terrain space is incrementally explored to maximize gains in locomotion robustness and performance. Can the Voronoi bias inherent in sampling-based planning steer the agent toward more effective and sample-efficient training trajectories? If successful, this approach could enable the use of real-world terrain scans for locomotion training, reducing dependence on expert-designed environments and substantially accelerating the training process. The project brings together concepts from sampling-based planning, adaptive curricula, and locomotion learning.

Keywords

Curriculum Learning, Quadruped Locomotion, Sampling-Based Planning, Reinforcement Learning

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Semester Project , Master Thesis

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Published since: 2025-12-10

Applications limited to ETH Zurich , EPFL - Ecole Polytechnique Fédérale de Lausanne , University of Zurich

Organization Robotic Systems Lab

Hosts Schwarke Clemens , Klemm Victor , Qu Kaixian

Topics Information, Computing and Communication Sciences

Simulator-Based Study of Camera Monitor Systems for Pedestrian Detection in Mobile Machinery

This project will develop and use a high-fidelity simulator to study how professional mobile-machine operators use Camera Monitor Systems (CMS) to detect pedestrians in hazardous zones. The student will help design and run an experimental study in which operators complete realistic trenching tasks using a virtual excavator while monitoring CMS feeds for pedestrians and responding to hazards. The data will then be used to develop a machine learning (ML) model that can predict safety performance and inform future CMS design.

Keywords

virtual reality; simulator study; Unity; eye-tracking; machine learning for safety and health;

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Published since: 2025-12-10 , Earliest start: 2025-12-10 , Latest end: 2026-10-01

Organization Biomedical and Mobile Health Technology Lab

Hosts Qi Shuaixin , Otesteanu Corin, Dr

Topics Medical and Health Sciences , Information, Computing and Communication Sciences , Engineering and Technology , Behavioural and Cognitive Sciences

Sign Language Interpreter

Sign language interpretation ensures communication remains inclusive, yet it is currently a task restricted to human experts. While modern humanoid hardware finally has the finger and arm dexterity to perform manipulation tasks, research exploring its applications in sign language communication is limited. We propose developing a control algorithm capable of listening to spoken language and translating it into sign language on a physical robot to act as an interpreter. In this project, you will focus on dynamic motion generation using reinforcement learning. This includes a variety of challenges from fields, requiring arm motion reconstruction from video, retargeting these poses to the robot’s morphology, training a robot to recreate these kinematic states, and then developing a method to receive text input to smoothly access this built motion vocabulary. You will then design a pipeline that can receive audio input from an interlocutor and feed these to the policy in real-time to effectively interpret the speech into sign language. You will be tackling challenges such as ensuring that words are being clearly formed by the robot and enabling smooth transitions between words.

Keywords

Humanoid robotics, learning from demonstration, reinforcement learning

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Published since: 2025-12-10

Organization Robotic Systems Lab

Hosts Wang Shengzhi , Mittal Mayank , Heyrman Matthias

Topics Information, Computing and Communication Sciences , Engineering and Technology

Predicting muscle forces from spinal alignment with machine learning - towards biomechanics-informed preoperative planning

How does patient alignment influence paraspinal muscle forces? In this project, we will explore these relationship analysing existing data and establishing a machine learning model to replace complex patient analyses, and bring biomechanics closer to clinical practise.

Keywords

Spine biomechanics, statistical analysis, machine learning

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Published since: 2025-12-10 , Earliest start: 2026-01-01 , Latest end: 2026-07-31

Organization Ferguson Group / Laboratory for Orthopaedic Technology

Hosts Ignasiak Dominika

Topics Mathematical Sciences , Information, Computing and Communication Sciences , Engineering and Technology

Gaussian Splatting Super Resolution

Radiance fields like 3D Gaussian Splatting enable fast, high-fidelity scene reconstruction from real-time data. However, reconstruction quality improves in noticeable stages—e.g., coarse at 500 epochs, detailed at 5000. This project explores whether AI-based upscaling and denoising techniques can be used to predict and accelerate these improvements during training. By anticipating reconstruction quality transitions, we aim to reduce training time while maintaining visual fidelity—advancing the efficiency of radiance field learning.

Keywords

Gaussian Splatting, Computer Vision, Reconstruction

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Published since: 2025-12-09 , Earliest start: 2025-11-01 , Latest end: 2026-07-31

Applications limited to ETH Zurich

Organization Robotic Systems Lab

Hosts Patil Vaishakh , Wilder-Smith Max

Topics Information, Computing and Communication Sciences

Walking Through Fog with Radar Splatting and RL

Help push the boundaries of robotic perception in foggy and visually degraded environments. This project focuses on enhancing the navigation capabilities of the quadruped robot Anymal using radar to perceive through fog. You'll simulate challenging conditions in NVIDIA IsaacLab and IsaacSim, generate clear 3D maps using 3D Gaussian Splatting, and train reinforcement learning-based navigation policies for real-world deployment. Combining advanced sensor fusion with cutting-edge RL, this project offers a hands-on opportunity to explore next-gen robotic vision and autonomy.

Keywords

Gaussian Splatting, Robotics, RL,

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Published since: 2025-12-09 , Earliest start: 2025-11-01 , Latest end: 2026-07-31

Applications limited to ETH Zurich

Organization Robotic Systems Lab

Hosts Wilder-Smith Max , Patil Vaishakh , Roth Pascal

Topics Information, Computing and Communication Sciences

Propose Your Own Robotics Project

This project invites you to step into the role of an innovator, encouraging you to identify challenges you are passionate about within the field of robotics. Rather than working on predefined problems, you will have the freedom to propose your own project ideas, address real-world issues, or explore cutting-edge topics. This project allows you to define your own research journey.

Keywords

Robotics, Research

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Published since: 2025-12-09 , Earliest start: 2025-01-27

Organization Robotic Systems Lab

Hosts Schwarke Clemens , Bjelonic Filip , Klemm Victor

Topics Information, Computing and Communication Sciences

Computational Modeling of Muscle Dynamics for Biohybrid Robots

This research aims to advance biohybrid robotics by integrating living biological components with artificial materials. The focus is on developing computational models for artificial muscle cells, a critical element in creating biohybrid robots. Challenges include modeling the complex and nonlinear nature of biological muscles, considering factors like elasticity and muscle fatigue, as well as accounting for fluid-structure interaction in the artificial muscle's environment. The research combines first principle soft body simulation methods and machine learning to improve understanding and control of biohybrid systems.

Keywords

Biohybrid Robotics, Computational Models, Soft Body Simulation, Finite Element Method (FEM), Muscle Dynamics, Soft Robotics

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Published since: 2025-12-09 , Earliest start: 2026-01-01 , Latest end: 2026-12-31

Organization Soft Robotics Lab

Hosts Mekkattu Manuel , Katzschmann Robert, Prof. Dr.

Topics Mathematical Sciences , Information, Computing and Communication Sciences , Engineering and Technology , Biology , Physics

GPU Acceleration of Soft Robot Modeling: Enhancing Performance with CUDA

We are enhancing soft robot modeling by developing a GPU-accelerated version of our FEM-based framework using CUDA. This research focuses on optimizing parallel computations to significantly speed up simulations, enabling larger problem sizes and real-time control. By improving computational efficiency, we aim to advance soft robotics research and facilitate more detailed, dynamic simulations.

Keywords

Soft Body Simulation, high-performance computing, GPU programming, Parallel Computing, Finite Element Method (FEM), Multiphysics Simulation

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Published since: 2025-12-09 , Earliest start: 2026-01-01 , Latest end: 2026-12-31

Organization Soft Robotics Lab

Hosts Katzschmann Robert, Prof. Dr. , Mekkattu Manuel

Topics Information, Computing and Communication Sciences , Engineering and Technology

Precision Positioning System for Miniature Specimens

This thesis develops an enhanced high-precision positioning concept for miniature tension test specimens by drawing on techniques from PCB assembly, micro-manipulation, and camera-based vision systems. The implemented approach is validated through prototype testing, demonstrating improved alignment accuracy and reproducibility compared to the current setup.

Keywords

Computer vision; Precision alignment; Micro-scale automation; Fiducial detection; Miniature specimen handling

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Published since: 2025-12-09 , Earliest start: 2026-01-05 , Latest end: 2026-10-31

Organization Computational Modelling of Materials in Manufacturing

Hosts Zwicker Ruben , Koltzenburg Nils

Topics Information, Computing and Communication Sciences , Engineering and Technology

Advancing Soft Robot Modeling: Integrating Physics, Optimization, and Control

We are advancing soft robot simulation with FEM and energy-based methods to model complex, adaptive behaviors. This research entails developing the framework to support diverse designs, integrate new physics models, and optimize performance, enabling enhanced control and real-world applications of soft robots.

Keywords

Soft Robotics, Finite Element Method (FEM), Physical Modeling, Benchmarking, Optimization, Multiphysics Simulation, Sim-to-Real

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Published since: 2025-12-09 , Earliest start: 2026-01-01 , Latest end: 2026-12-31

Organization Soft Robotics Lab

Hosts Mekkattu Manuel , Katzschmann Robert, Prof. Dr.

Topics Information, Computing and Communication Sciences , Engineering and Technology

Software Development: Enabling In Vitro Neuroscience Research

This project focuses on developing software for advanced neural interfaces used in in vitro studies. These interfaces enable precise exploration of neural activity, providing critical insights into neuronal dynamics, drug interactions, and neurological disorders. The project involves creating and optimizing software for data acquisition, analysis, and visualization, which directly enhances the usability and impact of these tools in research and healthcare applications. Ideal candidates will possess strong programming skills in Python. This project is available as Master thesis or semester project.

Keywords

Software development; Neural Interfaces; Neuroscience; Python; Biomedical Research; Neuroengineering; Neurotechnology.

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Published since: 2025-12-08 , Earliest start: 2025-12-14

Organization Bio Engineering Laboratory

Hosts Cardes Fernando

Topics Information, Computing and Communication Sciences

Multistable robotic tensegrities for dynamic shape-shifting

This thesis will combine robotic hardware prototyping with rigorous first principles-based modeling. The goal: tap into tensegrities’ nonlinear properties, such as multistability and instability, to realize robotic modules (bodies, arms, legs, etc.) that form the basis of dynamic shape-shifting systems.

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Published since: 2025-12-04 , Earliest start: 2026-01-01 , Latest end: 2026-08-01

Organization Robotic Systems Lab

Hosts Baines Robert

Topics Information, Computing and Communication Sciences , Engineering and Technology

Generative Environment Design: Using LLMs to bridge Sim-to-Real Gap for Locomotion

This project proposes an LLM-driven framework to automate the design of complex simulation environments for robust legged locomotion. By translating natural language descriptions directly into low-level physics parameters, we replace tedious manual tuning with semantic reasoning. The study focuses on training adaptive policies for quadrupedal or wheeled-legged robots, aiming to achieve robust performance across diverse, language-generated terrains.

Keywords

Large Language Models, Locomotion, Sim-to-Real, Domain Randomization, Physics Simulation, Reinforcement Learning.

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Published since: 2025-12-03

Organization Robotic Systems Lab

Hosts Palma Emilio , Roth Pascal

Topics Mathematical Sciences , Information, Computing and Communication Sciences , Engineering and Technology , Physics

Evaluation of muscle fatigue on paraspinal muscle activation patterns and spinal loads in patients with lumbar spinal stenosis

Lumbar spinal stenosis (LSS) is a condition characterized by a narrowing of the spinal canal, which can lead to compression of the lumbosacral nerve roots and/or the cauda equina. Clinical observations show that patients often adopt alternative postures and movement strategies to enlarge the spinal canal and relieve pain. These compensations likely require elevated paraspinal muscle activation may increase spinal segmental loads. Muscle fatigue may further increase compensatory posture, joint load and pain representing a vicious cycle. However, the specific implications of muscle fatigue on spinal loading in individuals with LSS remains insufficiently understood. The objective of this master thesis is to investigate how trunk muscle fatigue influences muscle recruitment patterns and spinal segmental loads in individuals with LSS. For this purpose, clinical data from 120+ patients with LSS - collected before and after a fatigue protocol - will be used to drive dynamic simulations of a full-body musculoskeletal model in the AnyBody Modeling System software.

Keywords

Spine biomechanics, musculoskeletal modeling, fatigue, trunk muscles

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Master Thesis , ETH Zurich (ETHZ)

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Published since: 2025-12-02 , Earliest start: 2026-02-01 , Latest end: 2026-07-31

Organization Musculoskeletal Biomechanics

Hosts Caimi Alice

Topics Engineering and Technology

Reinforcement Learning for Excavation Planning In Terra

We aim to develop a reinforcement learning-based global excavation planner that can plan for the long term and execute a wide range of excavation geometries. The system will be deployed on our legged excavator.

Keywords

Keywords: Reinforcement learning, task planning

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Published since: 2025-12-01 , Earliest start: 2026-02-01 , Latest end: 2026-09-30

Organization Robotic Systems Lab

Hosts Terenzi Lorenzo

Topics Information, Computing and Communication Sciences

Foundation models for generalizable construction machine automation

Autonomous operation of heavy construction machinery promises major gains in safety, efficiency, and scalability for the multi-trillion-dollar construction industry. Excavators present a unique challenge, combining the navigation demands of autonomous driving with the precision of robotic manipulation in unstructured, dynamic environments. This project explores Vision-Language-Action (VLA) and diffusion-based policy learning to develop generalizable excavation policies. Leveraging large-scale demonstration data naturally collected during human operation, we aim to train multimodal control models capable of adapting across sites, lighting conditions, and machine types. The approach will be evaluated through simulation benchmarks and, if possible, real-world trials, advancing the path toward scalable, generalist autonomy for robotic construction.

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Published since: 2025-12-01 , Earliest start: 2025-08-31 , Latest end: 2026-03-31

Applications limited to ETH Zurich , EPFL - Ecole Polytechnique Fédérale de Lausanne

Organization Robotic Systems Lab

Hosts Nan Fang , Zhang Weixuan

Topics Engineering and Technology

Perceptive Generalist Excavator Transformer

We want to develop a generalist digging agent that is able to do multiple tasks, such as digging and moving loose soil, and/or control multiple excavators. We plan to use a decoder only GPT model, trained on offline data and potentially online RL as posttraining, to accomplish these tasks.

Keywords

Offline reinforcement learning, transformers, autonomous excavation

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Published since: 2025-12-01 , Earliest start: 2026-02-01 , Latest end: 2026-10-31

Organization Robotic Systems Lab

Hosts Werner Lennart , Terenzi Lorenzo , Nan Fang

Topics Information, Computing and Communication Sciences

Reinforcement Learning for Particle-Based Excavation in Isaaclab / Newton

We want to train RL agents on our new particle simulator, accelerated on the GPU via warp in Isaaclab and Newton.

Keywords

particle simulation, omniverse, warp, reinforcement learning

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Published since: 2025-12-01 , Earliest start: 2025-06-01 , Latest end: 2025-12-31

Organization Robotic Systems Lab

Hosts Terenzi Lorenzo

Topics Information, Computing and Communication Sciences

Automated Design and Additive Manufacturing of Bending Jigs for Induction Coil Fabrication

Induction heating is used in soldering applications where fast, efficient and localized heating is necessary. Examples include the repair of photovoltaic modules and soldering of smart textiles. Heat is introduced in the solder joint through electromagnetic induction, where high frequency excitation of a coil is used to induce current in the solder pad. Coil for these applications are often bent from copper tube, to allow for internal water cooling. Coils are often application-specific and therefore manually produced by bending. This process depends on a skilled fabricator, and results are often not reproducible. The idea of this thesis is to use automatically generated bending jigs that can be additively manufactured. A design automation workflow should be developed that generates the necessary jigs based on a given coil geometry without manual intervention. The jigs should then be evaluated by using them to manufacture various coils.

Keywords

Design automation, additive manufacturing, 3D-printing, induction heating, hands-on

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Published since: 2025-12-01

Organization pd|z Product Development Group Zurich

Hosts Ritter Simon

Topics Engineering and Technology

Self-Supervised LiDAR–RGB Encoders for Autonomous Earthworks

This project adapts recent self-supervised 3D and 2D–3D representation learning methods (Sonata/Concerto-style encoders) to build a robust LiDAR–RGB backbone for earthmoving robots. The goal is a reusable encoder that powers perception for excavation, loading, traversability, and safety on real construction sites, and runs in real time on our robots.

Keywords

LiDAR–RGB fusion, Self-supervised learning, 2D–3D representations, Earthmoving robotics, Perception

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Published since: 2025-12-01 , Earliest start: 2026-02-01 , Latest end: 2026-08-31

Organization Robotic Systems Lab

Hosts Terenzi Lorenzo

Topics Engineering and Technology

RL Finetuning for Generalized Quadruped Locomotion

This project investigates the potential of reinforcement learning (RL) fine-tuning to develop a single, universal locomotion policy for quadruped robots. Building on prior work in multi-terrain skill synthesis [1], we will probe the limits of generalization by systematically fine-tuning on an ever-expanding set of diverse environments. This incremental approach will test the hypothesis that a controller can learn to robustly navigate a vast range of terrains. As a potential extension, procedural terrain generation may be used to automatically create novel challenges, pushing the boundaries of policy robustness.

Keywords

Reinforcement Learning, Quadruped Locomotion

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Published since: 2025-11-28 , Earliest start: 2025-06-15

Organization Robotic Systems Lab

Hosts Schwarke Clemens , He Junzhe

Topics Information, Computing and Communication Sciences

Hardware Support HiWi

Mechanical Design, Integration, Robot repairs

Keywords

Hardware, Design, Mechanics, CAD

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Published since: 2025-11-28 , Earliest start: 2025-12-01

Organization Robotic Systems Lab

Hosts Krasnova Elena

Topics Engineering and Technology

Data-Driven Health Indicators and RUL Forecasting for Mechanical Systems

This thesis explores data-driven methods for assessing the health and forecasting the remaining useful life (RUL) of complex mechanical systems using benchmark datasets such as NASA C-MAPSS, N-C-MAPSS, FEMTO/PRONOSTIA and XJTU-SY. The student will develop health indicators by modelling nominal system behaviour with recurrent and operator-learning architectures, and use these indicators to track degradation over time. Building on this, the project involves training uncertainty-aware RUL models and evaluating their calibration, interpretability, and suitability for deployment. The outcome is an integrated predictive-maintenance workflow combining health assessment, degradation tracking, and reliable RUL forecasting.

Keywords

predictive maintenance, remaining useful life, neural operators, condition monitoring, degradation modelling

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Published since: 2025-11-27 , Earliest start: 2026-01-15 , Latest end: 2026-08-31

Organization Structural Mechanics (Prof. Chatzi)

Hosts Chatzi Eleni

Topics Engineering and Technology

Mechanophores for advanced wearable strain and pressure sensors

The goal of the project is to synthesize and characterize a number of small molecules capable of acting as mechanophore addition to various polymers. These polymers would then be used as wearable strain or pressure sensors.

Keywords

mechanophore, polymer, wearable, sensor, color, strain, pressure

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Published since: 2025-11-27

Organization Biomedical and Mobile Health Technology Lab

Hosts Shokurov Aleksandr

Topics Engineering and Technology , Chemistry

Hybrid Modeling for Twinning and Structural Health Monitoring in Engineered Systems

Ensuring the safe, efficient, and resilient operation of structural assets throughout their life cycle relies on the integration of sensing data with computational models that are both rapid to evaluate and reliable. This hybrid paradigm is particularly vital in the operation and maintenance of structures that operate under high variability and may experience damage or extreme events that push their response far beyond design assumptions. In this context, this thesis will focus on deriving actionable and flexible hybrid representations and demonstrate the potential they offer towards digital twinning offer for the optimized operation & maintenance of real-life structural systems.

Keywords

Structural Health Monitoring; Digital Twins; Machine Learning; Surrogate Modelling; Data Assimilation; Inverse Problems;

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Published since: 2025-11-27 , Earliest start: 2026-02-01 , Latest end: 2026-08-31

Organization Structural Mechanics (Prof. Chatzi)

Hosts Vlachas Konstantinos , Chatzi Eleni

Topics Engineering and Technology

Augmented Reality-assisted Finite Element Analysis

Augmented reality (AR) has revolutionized the video game industry via developing interactive, three-dimensional visualizations of physical processes or life-like environments. Building upon existing tools and previous project work, the aim of this thesis is twofold: First, to develop a visualization pipeline that allows users to experience and assess Finite Element Analysis results in an immersive, holographic environment. Second, to enable user interaction with the modeling software via the AR environment, thus enabling the user to calibrate the underlying model or request additional parametric analyses.

Keywords

Augmented Reality; Structural Dynamics; Finite Element Analysis;

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Published since: 2025-11-27 , Earliest start: 2026-02-01 , Latest end: 2026-08-31

Organization Structural Mechanics (Prof. Chatzi)

Hosts Chatzi Eleni , Vlachas Konstantinos

Topics Engineering and Technology

Point-of-Care Sensor for Urinary Iodine

The goal of the project is to develop a cheap and disposable sensor capable of determination of iodine levels in human urine for early diagnostic purposes.

Keywords

electrochemistry, iodine, nutrition, health, point of care

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Published since: 2025-11-27

Organization Biomedical and Mobile Health Technology Lab

Hosts Shokurov Aleksandr

Topics Medical and Health Sciences , Engineering and Technology , Chemistry

Close-Proximity Human-Aware Locomotion

In order to safely navigate a quadrupedal robot through a dense crowd, two conditions need to be satisfied: (1) The robot body does not collide with any of the people in the scene, and (2) the robot does not step on anyone’s feet. The goal of this thesis is to train a locomotion policy that can safely traverse environments with dynamically moving bodies. The problem is treated as an inverse stepping-stone problem, using binary segmentation of the human (foot) areas to create forbidden zones within the elevation map.

Keywords

Robotics, Reinforcement Learning, Crowd Navigation, Human-Robot Interaction

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Published since: 2025-11-27 , Earliest start: 2026-02-01 , Latest end: 2026-10-31

Organization Robotic Systems Lab

Hosts Scheidemann Carmen

Topics Information, Computing and Communication Sciences

Engineering of Gastroretentive Drug Delivery systems

Polymer-based drug delivery systems play a central role in shaping modern therapeutics, offering controlled release behavior and improved patient compliance. Yet traditional formulation development still relies largely on resource-intensive and time-consuming iterative experimentation to balance the complex interactions between polymer composition, processing parameters, and drug release behavior. This project aim to solve these limitations by developing a machine learning (ML) algorithm to accelerate the rational design of polymer formulations tailored to specific release profiles. By integrating active ingredient’s encapsulation studies, rheological and mechanical analyses, and detailed release-kinetic profiling, the work aims to build a comprehensive understanding of how formulation variables govern functional performance. The resulting dataset will later support data-driven modelling, enabling faster identification of promising compositions. This approach not only streamlines pharmaceutical development but also advances sustainable practices by minimizing material waste, positioning data-driven formulation as a cornerstone of next-generation smart therapeutics. This project focuses on the optimization and characterization of a novel gastroretentive drug delivery system (GARD) loaded with a selection of active compounds from a pre-established library of molecules. Comprehensive chemical and mechanical analyses will be conducted, encompassing encapsulation efficiency, rheological behavior, drug release kinetics, and the stability of encapsulated active pharmaceutical ingredients (APIs). A curated dataset of API-loaded polymer formulations and their associated properties will be later used to train predictive models, enabling the identification of optimal formulations with tailored release profiles.

Keywords

Drug Delivery Polymer formulation Advanced manufacturing Machine learning

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Published since: 2025-11-26 , Earliest start: 2025-12-01 , Latest end: 2026-12-31

Applications limited to Balgrist Campus , EPFL - Ecole Polytechnique Fédérale de Lausanne , ETH Zurich , Fernfachhochschule , Zurich University of Applied Sciences , University of Zurich , University of Basel , University of Berne , Institute for Research in Biomedicine , Hochschulmedizin Zürich , Empa

Organization Macromolecular Engineering Laboratory

Hosts Guzzi Elia

Topics Medical and Health Sciences , Engineering and Technology , Chemistry

Exploring Applications of Physical Computing to Condition and Structural Health Monitoring

This thesis explores the emerging field of physical computing for condition and structural health monitoring. Recent advances in mechanical metamaterials and MEMS devices have enabled physical signal processing, where a device’s intrinsic dynamics—such as resonance responses—are used to classify complex acoustic inputs with near-zero power consumption. Building on this concept, the project investigates how acoustic emission (AE) signals from damage in composite structures can be identified and classified using MEMS-based physical computing architectures. The student will analyze real AE datasets, extract key signal features, and develop an in-silico training and validation environment for a mechanical classifier. Ultimately, this work contributes toward low-cost “smart-dust” devices capable of passively monitoring structural integrity when remotely interrogated.

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Published since: 2025-11-26 , Earliest start: 2026-02-01 , Latest end: 2026-08-31

Organization Structural Mechanics (Prof. Chatzi)

Hosts Chatzi Eleni

Topics Engineering and Technology

Free-Viewpoint Teleoperation via Dynamic Gaussian Splatting

Immersive teleoperation should feel natural and precise—like reaching in with your own hands. Most prior work shows this only in static scenes, where the operator guides a robot to an object without truly changing the world [1]. Real tasks aren’t that simple: the moment you grasp, move, or reorient something, the scene changes. If the 3D view doesn’t update, depth cues fade, confidence drops, and mistakes creep in. We propose a single-arm teleoperation system that keeps the 3D world live. Using 3D Gaussian Splatting, the scene is continuously refreshed as objects move, so what you see in VR matches what the robot sees right now. With just a wrist camera and small, smart arm adjustments to avoid occlusions (no extra camera arm), the operator keeps a clear view of the action. In VR, you can pick helpful viewpoints on the fly, working with a photorealistic, always-current reconstruction that boosts precision, speed, and confidence. Moreover, you will get hands-on time with the real robot (you really do get to play with it), with proper safety and supervision. Strong results may also lead to a conference or journal paper submission at the end of the project.

Keywords

Dynamic Gaussian Splatting, Teleoperation, Robotics

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Published since: 2025-11-25 , Earliest start: 2025-12-01 , Latest end: 2026-06-01

Applications limited to ETH Zurich

Organization Robotic Systems Lab

Hosts Wilder-Smith Max , Wang Shengzhi , Patil Vaishakh

Topics Information, Computing and Communication Sciences , Engineering and Technology

Design and control of a bio-inspired tensegrity robot leg

This hardware-focused thesis will build a robotic leg from tensegrity structures, taking the first steps to realizing a new class of dynamic legged robot.

Keywords

Robotics, Quadrupeds, Control, Tensegrity, Mechanics, Design

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Published since: 2025-11-25 , Earliest start: 2026-01-01 , Latest end: 2026-11-01

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Organization Robotic Systems Lab

Hosts Baines Robert

Topics Information, Computing and Communication Sciences , Engineering and Technology

Spatial Proteomics of Mechanically-Driven Bone Healing

Bone healing is profoundly influenced by its mechanical environment. Advances in spatial proteomics now allow us to map protein expression within intact tissue and directly relate it to local biomechanical cues. The Laboratory for Bone Biomechanics is developing a new line of research within spatial mechanomics (DOI: 10.1126/sciadv.adp8496), integrating spatially resolved proteomic data with in silico models of the mechanical environment at fracture sites. This approach enables us to investigate, at cellular resolution, how mechanical forces shape protein-level signalling during bone repair.

Keywords

Bone, Mechanobiology, Spatial Proteomics, Protein Expression, Aging, Sex Differences, Mechanical Loading, Finite Element Modelling, Image Analysis

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Published since: 2025-11-23 , Earliest start: 2025-12-01 , Latest end: 2026-12-31

Organization Müller Group / Laboratory for Bone Biomechanics

Hosts Mathavan Neashan

Topics Medical and Health Sciences , Engineering and Technology , Biology

Tactile Sensing and Model-Based RL for Contact-Aware Control in Soft Robots

Soft robotic manipulators excel in safe, compliant motion, but controlling them during contact-rich interactions remains a major challenge. This project aims to develop contact-aware control for a tendon-driven soft robotic arm by combining vision-based tactile sensing with model-based reinforcement learning (MBRL).

Keywords

soft robotics, tendon-driven actuation, capacitive sensing, model-based RL, contact-rich control

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Master Thesis , ETH Zurich (ETHZ)

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Published since: 2025-11-19 , Earliest start: 2026-01-15 , Latest end: 2026-12-31

Organization Soft Robotics Lab

Hosts Zheng Hehui

Topics Information, Computing and Communication Sciences , Engineering and Technology

Reduced-Order Modeling for Density-Based Topology Optimization

This Master's Thesis opportunity is jointly offered by the Chair of Structural Mechanics & Monitoring at ETH Zürich (Prof. Dr. Eleni Chatzi) and by the Group of Engineering Dynamics at ETH Zürich (Dr. Paolo Tiso). Topology optimization is a powerful tool for determining optimal material distribution, but its iterative nature leads to substantial computational costs, especially for large-scale problems. On the other hand, its high-dimensional design space poses unique challenges to apply conventional surrogate modeling techniques, such as Reduced-Order Models. This thesis investigates methodologies to tackle these challenges, thus providing a framework for accelerated topology optimization routines.

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Reduced-Order Modeling, topology optimization, surrogate models, machine learning

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Published since: 2025-11-18 , Earliest start: 2026-02-01 , Latest end: 2026-08-31

Organization Structural Mechanics (Prof. Chatzi)

Hosts Chatzi Eleni , Betti Federico , Tiso Paolo

Topics Mathematical Sciences , Engineering and Technology

Mini-muscle gym: Developing a Broad-field Electrical and Mechanical Stimulation Device for Biohybrid Robots

Biohybrid robotics seeks to replace conventional actuator materials with engineered muscle to harness the adaptability and efficiency of biological systems. A major challenge, however, remains the limited force output of engineered skeletal muscle tissues. This project aims to address that limitation through the development of an electrical stimulation system integrated into a muscle-maturation platform ("mini-muscle gym") designed to enhance tissue strength via mechanical and electrical cues. The work will involve circuit and PCB design, implementation within an existing mechanical framework, and close collaboration with tissue engineers to meet biological requirements. The resulting thesis will form an interdisciplinary contribution at the interface of engineering and biology. See attached pdf for further details and references.

Keywords

Biohybrid robotics, soft robotics, circuit design, signal generation, biomaterials, electrical stimulation, mechanical stimulation, actuation, tissue engineering, muscle tissue, muscle cells.

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Semester Project , Bachelor Thesis , Master Thesis

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Published since: 2025-11-17 , Earliest start: 2025-11-24 , Latest end: 2026-07-31

Organization Soft Robotics Lab

Hosts Balciunaite Aiste , Paniagua Pablo

Topics Engineering and Technology

Perceptive object pushing with a quadrupedal manipulator

Legged manipulators combine the mobility of legged robots with the dexterous interaction capabilities of robotic arms. Recent research has demonstrated a variety of skills on such systems using reinforcement learning (RL) controllers trained in simulation. In our previous work [1], we showcased contact-rich, non-prehensile mobile manipulation, where a legged robot was able to move and reorient unknown objects through pushing actions. However, this approach depends on an external motion-capture system to track the object’s 6D pose, a major limitation for real-world and field deployment. This project aims to overcome that challenge by developing a perceptive control policy that performs nonprehensile object manipulation using only onboard sensing. A particularly promising direction is to leverage onboard RGB cameras to provide rich visual feedback regarding both the position and orientation of the object in real time [2]. End-to-end RL (perception to action) and/or teacher-student distillation [3] approaches will be investigated. Through this project, the student will gain extensive hands-on experience in RL, sim-to-real transfer, perception for learning-based control and mobile manipulation. References: 1. Dadiotis et al, “Dynamic object goal pushing with mobile manipulators through model-free constrained reinforcement learning”, ICRA 2025 2. Qureshi et al, “SplatSim: Zero-Shot Sim2Real Transfer of RGB Manipulation Policies Using Gaussian Splatting”, ICRA 2025. 3. Singh et al, “DextrAH-RGB: Visuomotor Policies to Grasp Anything with Dexterous Hands”. arXiv 2024.

Keywords

End-to-end RL, Perceptive Manipulation, Mobile Manipulation

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Master Thesis

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Published since: 2025-11-16 , Earliest start: 2026-01-15 , Latest end: 2026-10-31

Organization Robotic Systems Lab

Hosts Bhardwaj Arjun , Dadiotis Ioannis

Topics Information, Computing and Communication Sciences

Response Inference in Evolving Conditions via Hypernetworks and Online Learning

Engineering dynamical systems operate under variability and continuously changing conditions. This poses unique requirements when designing twin representations, necessitating the adaptive updating of underlying models in real-time. This thesis aims to address this challenge via the use of hypernetworks for forecasting under variability and their fusion with online and active learning techniques. Thus, this work focuses on developing efficient update mechanisms that allow already trained and deployed surrogates to adapt to sensing data while minimizing computational cost and required measurements. The framework will be validated on benchmark dynamical systems with time-varying parameters and applied to real-world case studies.

Keywords

Hypernetworks; Scientific Machine Learning; Nonlinear Dynamics; Computational Modeling;

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Master Thesis , ETH Zurich (ETHZ)

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Published since: 2025-11-14 , Earliest start: 2026-02-01 , Latest end: 2026-08-31

Organization Structural Mechanics (Prof. Chatzi)

Hosts Vlachas Konstantinos , Chatzi Eleni

Topics Engineering and Technology

Push or pull? Unifying mobile manipulation skills for a quadrupedal manipulator

This thesis will focus on unifying multiple different mobile manipulation skills into a single controller for mobile manipulation with a quadrupedal manipulator

Keywords

mobile manipulation, robotics, control, reinforcement learning, quadrupedal manipulation

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Master Thesis

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Published since: 2025-11-14 , Earliest start: 2026-01-07

Organization Robotic Systems Lab

Hosts An Tianxu , Dadiotis Ioannis

Topics Information, Computing and Communication Sciences , Engineering and Technology

Upcycling of Ti machining waste for sustainable solid state (additive) manufacturing—a life cycle analysis

You will evaluate the sustainability impact of novel circular processing routes that convert Ti swarf into low-cost powders for powder-metallurgical manufacturing, e.g., sintering or additive manufacturing, and compare these to standard primary and secondary synthesis routes.

Keywords

additive manufacturing; powder metallurgy; sustainability; life cycle analysis; economics; titanium

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Semester Project , Internship , Bachelor Thesis , Master Thesis , Master Project (D-MATL)

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Published since: 2025-11-13 , Earliest start: 2026-02-01 , Latest end: 2026-12-31

Organization Nanometallurgy

Hosts Reiser Alain

Topics Engineering and Technology , Economics

Computational modeling of reactive multiphase flow processes

This project employs numerical modeling of reactive multiphase flow and transport processes relevant to a wide range of engineering and environmental systems. Using computational fluid dynamics (CFD) and custom numerical tools, the work aims to simulate coupled flow, transport, and reaction phenomena in porous and non-porous materials.

Keywords

Numerical simulations; Flow and transport; Computational fluid dynamics (CFD); Porous media; Building materials; Corrosion; Material degradation; Computational modeling; Reactive processes

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Semester Project , Master Thesis

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Published since: 2025-11-11

Organization Durability of Engineering Materials (Prof. Angst)

Hosts Malenica Luka

Topics Agricultural, Veterinary and Environmental Sciences , Mathematical Sciences , Information, Computing and Communication Sciences , Engineering and Technology , Earth Sciences , Chemistry , Physics

Characterizing the Contraction Dynamics of Tissue Engineered Skeletal Muscle Constructs for Biohybrid Robots

Soft robotics is moving toward the use of biological materials, such as muscle tissue, to create biohybrid actuators that harness the adaptability and efficiency of living systems. However, the lack of accurate computational models for muscle contraction limits rational design, making development heavily reliant on trial and error. This project contributes to a sim-to-real pipeline for biohybrid muscle design, focusing on fabrication and experimental characterization of actuators. Students will gain experience in skeletal muscle culture, confocal microscopy, calcium imaging, and force measurements, resulting in an interdisciplinary thesis bridging mechanical engineering and biology.

Keywords

Biohybrid robotics, soft robotics, 3D printing, biomaterials, tissue engineering, muscle tissue, muscle cells, bioprinting, biofabrication, electrical stimulation, actuation, material characterization.

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Semester Project , Bachelor Thesis , Master Thesis

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Published since: 2025-11-11 , Earliest start: 2025-11-28 , Latest end: 2026-07-31

Organization Soft Robotics Lab

Hosts Balciunaite Aiste , Katzschmann Robert, Prof. Dr.

Topics Engineering and Technology

Learning Dexterous Robotic Manipulation from Human Demonstrations

The goal of this project is to endow a robotic arm-hand system with the ability to complete everyday-life tasks like using tools, opening doors, or assembling equipment. This skill will have important implications across a range of domains, including personal robotics, manufacturing, and fulfillment.

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Master Thesis

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Published since: 2025-11-11 , Earliest start: 2025-11-16 , Latest end: 2026-08-31

Organization Computational robotics laboratory (Prof. Stelian Coros)

Hosts Coros Stelian

Topics Information, Computing and Communication Sciences

3-Dimensional Convolutional Neural Network for semantic segmentation

X-ray micro-computed tomography is an imaging technique enabling interior characterization of material micro-structures. The incident waves penetrate through the sample and are attenuated by the material density to be absorbed by a detector, represented by a quantized greyscale value. By rotating the sample and iteratively recording radiographic projections, internal boundaries between material phases can be retrieved. To recover quantifiable information regarding the sample, it is crucial to accurately perform semantic segmentation on the computed tomographs. Semantic segmentation refers to the categorization of each individual pixel within an image (voxel in 3D) into bins representing the various respective materials within the original data. Semantic segmentation poses relevance to a wide variety of computer vision and image analysis fields including autonomous driving, biomedical diagnosis, and agricultural analytics. Typical semantic segmentation often utilizes regional texture and color analysis or pixel distribution methods (Gaussian mixture and K-means) to determine pixel classification. These methods are highly reliable yet often are not time efficient on large datasets. Additionally, specific tuning is required for differing samples.

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Machine Learning; X-ray imaging; Material characterization

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Published since: 2025-11-10 , Earliest start: 2026-01-12 , Latest end: 2026-05-29

Organization Group Supponen

Hosts Brewer Cameron

Topics Engineering and Technology

Catalytic Degradation of PFAS in water

Per- and polyfluoroalkyl substances (PFAS) represent a persistent class of contaminants of emerging concern in water systems, requiring advanced treatment solutions beyond conventional processes. This master’s thesis project investigates catalytic degradation pathways for PFAS in aqueous environments, integrating material synthesis, catalyst characterization, and treatment optimization. Students will fabricate and analyze novel catalyst materials, evaluate degradation performance under varied operational conditions, and assess the system’s applicability using real-water matrices. Conducted at the Australian Centre for Water and Environmental Biotechnology (ACWEB) at The University of Queensland, the project combines material science, environmental engineering, and analytical chemistry to advance PFAS remediation methodologies.

Keywords

PFAS degradation; catalytic treatment; water purification; material synthesis; environmental nanotechnology; LC-MS analysis; fluoride quantification; advanced oxidation; water quality engineering.

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Master Thesis , Other specific labels , ETH Zurich (ETHZ)

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Published since: 2025-11-10 , Earliest start: 2026-01-01 , Latest end: 2026-12-31

Organization Multiscale Robotics Lab

Hosts Gantenbein Valentin

Topics Engineering and Technology

K-wave simulation of non-linear effects on HIFU transducer wave propagation

High intensity focused ultrasound is a non-invasive biomedical treatment for tissue ablation. Through the propagation of high intensity pressure waves, tissue material can be destroyed by thermal effects or cavitation damage in a pulsed signal. The approach is utilized in treatment of tumours in many parts of the body including breast, kidney, liver, and prostate. The high intensity of the incident wave leads to a non-constant speed of sound within the medium generating non-linearity effects on the wave. Wave non-linearity inherently shifts wave energy to higher harmonics, influencing bubble stability and cavitation threshold. A past student project has used K-wave (a Matlab package) to simulate the pressure field of an ultrasound transducer, focusing on signal reflection and distortion resulting from impeding objects within the propagation field. This project builds upon the previously completed work by incorporating non-linearity in the simulation focusing on high intensity burst waves and enables efficient transducer design by simulating the change in the pressure signal as the number of transducer elements and configuration are manipulated.

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Nonlinear acoustics; Numerical simulation; Code optimization

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Published since: 2025-11-10 , Earliest start: 2026-01-12 , Latest end: 2026-05-29

Organization Group Supponen

Hosts Brewer Cameron

Topics Engineering and Technology

AI-Based Blood Pressure Estimation from PPG Signals Using Wearable Devices

This project explores the feasibility of measuring blood pressure using pulse travel time (PTT) between two photoplethysmography (PPG) sensors, validated against ground truth blood pressure cuff measurements, employing machine learning and computational models.

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machine learning, artificial intelligence, generative AI, photoplethysmography (PPG), smart-watch, wearable devices, blood pressure

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Semester Project , Master Thesis

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Published since: 2025-11-06 , Earliest start: 2025-12-01 , Latest end: 2026-09-01

Organization Biomedical and Mobile Health Technology Lab

Hosts Otesteanu Corin, Dr

Topics Information, Computing and Communication Sciences , Engineering and Technology

Light-Driven CO₂ Capture via a Photodynamic pH-Swing Process

Direct air capture (DAC) of CO₂ is a key technology for achieving carbon neutrality, yet its large-scale deployment is limited by the high energy required for CO₂ release. At the Electrochemical Energy Systems Laboratory (Prof. Maria Lukatskaya), we are developing a novel, sunlight-driven pH-swing process that uses light to modulate solution acidity and minimize energy input for sorbent regeneration. The project focuses on the design, synthesis, and characterization of photoactive merocyanine molecules capable of reversibly altering their protonation state under light irradiation. These compounds enable alternating high- and low-pH conditions in aqueous media, allowing CO₂ capture in the dark and its controlled release upon illumination.

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Photoacids; Micelles; pH control; CO2 capture; Light-responsive systems

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Published since: 2025-11-06

Organization Laboratory for Electrochemical Energy Systems

Hosts Scapin Joseph

Topics Chemistry

Shape oscillations of bubbles on an oscillating surface

When a microbubble resting on a surface is excited around its resonance frequency, the bubble exhibits intense shape deformations. This project aims at designing an experimental setup to capture the surface instabilities of accelerated bubbles.

Keywords

Fluid dynamics, bubbles, instability

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Semester Project , Bachelor Thesis , ETH Zurich (ETHZ)

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Published since: 2025-11-06 , Earliest start: 2026-01-01 , Latest end: 2026-06-30

Applications limited to Department of Mechanical and Process Engineering

Organization Group Supponen

Hosts Presse Louan

Topics Engineering and Technology

PCB Design for in Vitro Neural Interfaces

This project centers on designing and developing high-speed printed circuit boards (PCBs) for advanced CMOS microelectrode arrays (MEAs) used in in vitro neuroscience research. These PCBs are critical for interfacing with neural tissue, enabling precise control and data acquisition from high-density electrode arrays. The project involves schematic design, layout, signal integrity optimization, and testing of PCBs operating at ~100 MHz. Ideal candidates will have experience with Altium Designer and a strong foundation in electronics and signal processing.

Keywords

PCB Design; CMOS MEA; Altium; Signal Integrity; Neurotechnology; Neural interface; BCI; Neuroscience

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Semester Project , Bachelor Thesis , Master Thesis , ETH Zurich (ETHZ)

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Published since: 2025-10-30 , Earliest start: 2025-10-31

Organization Bio Engineering Laboratory

Hosts Cardes Fernando

Topics Engineering and Technology

Design and Evaluation of a Signature Circuit for Secure Chip Integration

This project focuses on the design and evaluation of a signature circuit intended for secure integration into a chip. The student will explore different architectural interpretations, implement cryptographic primitives such as hashing and encryption, and assess the circuit’s performance and security. The goal is to identify the most effective design for real-world deployment in secure hardware.

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VLSI; Cryptography; Hardware Security; RTL Design; HDL; Key Management; Secure Systems; Cybersecurity;

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Published since: 2025-10-30 , Earliest start: 2025-10-31

Organization Bio Engineering Laboratory

Hosts Cardes Fernando

Topics Information, Computing and Communication Sciences , Engineering and Technology

Spatially-Enhanced Linear-Attention Transformer for End-to-End Navigation

Transformer architectures have proven highly effective in sequence modelling, but their standard self-attention mechanism suffers from quadratic complexity in sequence length. The work by Transformers are RNNs: Fast Autoregressive Transformers with Linear Attention (Katharopoulos et al., 2020) shows how self-attention can be reformulated as kernel feature maps with a linear complexity implementation. Separately, in navigation and robotics, end-to-end learning of navigation policies (e.g., via reinforcement learning) has shown strong promise; however, many architectures (such as standard RNNs) struggle to build spatial memory — that is, integrating observations from different viewpoints into a coherent spatial representation. For example, the recent work Spatially‑Enhanced Recurrent Memory for Long‑Range Mapless Navigation via End‑to‑End Reinforcement Learning (Yang et al., 2025) proposes Spatially-Enhanced Recurrent Units (SRUs) to address this. This motivates the question: can we combine the efficiency and scalability of linear-attention transformers with a spatial-enhancement mechanism tailored for navigation, thereby achieving end-to-end navigation with long-term spatial memory and efficient inference?

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Semester Project , Master Thesis , ETH Zurich (ETHZ)

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Published since: 2025-10-28 , Earliest start: 2025-11-15 , Latest end: 2025-12-15

Organization Robotic Systems Lab

Hosts Yang Fan

Topics Information, Computing and Communication Sciences

Microbubble characterization through acoustic radiation force

Acoustically driven microbubbles could unlock local drug delivery in a clinical setting. This therapy requires a precise characterization of the microbubble volumetric oscillations. This project will investigate an alternative method to characterize the volumetric oscillations indirectly through the acoustic radiation force. For this, the student is expected to conduct experiments and compare them with the predictions from theoretical models.

Keywords

Biomedical, drug delivery, ultrasound contrast agents, physics, experimental

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Published since: 2025-10-28 , Earliest start: 2025-12-01

Applications limited to ETH Zurich

Organization Group Supponen

Hosts Collado Gonzalo

Topics Engineering and Technology , Physics

Hand Gesture Recognition Using High-Density Surface Electromyography (HD-sEMG

The project aims to develop machine learning models for real-time hand gesture recognition using high-density surface electromyography (HD-sEMG) signals. This research focuses on improving neuroprosthetic control and rehabilitation by accurately decoding hand movements from HD-sEMG data.

Keywords

HD-sEMG, neuroprosthetics, biosignal monitoring, machine learning, hand gesture recognition, rehabilitation

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ETH Zurich (ETHZ)

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Published since: 2025-10-20

Organization Biomedical and Mobile Health Technology Lab

Hosts Qi Shuaixin

Topics Medical and Health Sciences , Information, Computing and Communication Sciences , Engineering and Technology

Gait and Posture Analysis Using Multimodal Data from Smart Walkers

The project aims to develop machine learning models to analyze gait and posture using multimodal data collected from participants using a robotic walker equipped with multiple cameras and inertial sensors. This research focuses on detecting abnormalities in gait patterns and postural control, contributing to the development of rehabilitation and assistive technologies.

Keywords

gait analysis, posture monitoring, smart walker, motion capture, biomechanics, sensor fusion, rehabilitation, inertial sensors

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ETH Zurich (ETHZ)

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Published since: 2025-10-20

Organization Biomedical and Mobile Health Technology Lab

Hosts Qi Shuaixin

Topics Medical and Health Sciences , Information, Computing and Communication Sciences , Engineering and Technology

Detection of Cardiovascular Abnormalities from Paper ECG Images Using Deep Learning

This project aims to develop a deep learning algorithm to detect and classify cardiovascular abnormalities directly from paper-based or image-scanned ECGs. By bypassing the need for full digitization, the objective is to enable rapid diagnosis and improve access to cardiovascular healthcare, particularly in resource-limited settings.

Keywords

ECG, cardiovascular disease, image classification, deep learning, global health, medical imaging, underserved populations

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ETH Zurich (ETHZ)

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Published since: 2025-10-20

Organization Biomedical and Mobile Health Technology Lab

Hosts Qi Shuaixin

Topics Medical and Health Sciences , Information, Computing and Communication Sciences , Engineering and Technology

Prevention and Treatment of Chronic Intestinal Leakages – Enteroatmospheric Fistulas

Our project aims to develop a novel therapeutic and preventive approach for Enteroatmospheric Fistulas. A first functional prototype has already been developed, and now, we are excited to work with you and advance it further.

Keywords

Surgery, Surgical Technology, Innovation, Materials Science, 3d printing.

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Semester Project , Internship , Master Thesis

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Published since: 2025-10-20 , Earliest start: 2025-11-01 , Latest end: 2027-09-30

Applications limited to ETH Zurich , EPFL - Ecole Polytechnique Fédérale de Lausanne , University of Zurich , Wyss Translational Center Zurich , University of Berne , University of Geneva , University of Basel

Organization Nanoparticle Systems Engineering Laboratory

Hosts Herrmann Inge

Topics Engineering and Technology

Hardware / software development in medtech startup (project / thesis)

diaxxo, a start-up from ETH Zürich, is transforming molecular diagnostics with an innovative Point-of-Care Polymerase Chain Reaction (PCR) device. Designed to accelerate and democratize access to diagnostic testing, our cutting-edge technology can be used across various fields, from human diagnostics to vet and food testing. Our products are also tailored for use in developing countries and resource-limited settings, aiming to bring reliable diagnostics to every corner of the globe. The company offers several projects and thesis opportunities focusing on interfacing computer and camera systems (e.g. controlling Camera Pi from ESP microcontrollers, and integrating hardware and software components to address design and automation challenges.

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Point-of-Care PCR, Molecular Diagnostics, Embedded Systems, Arducam SPI, Camera Pi ESP Microcontroller, Hardware-Software Integration, Design and Automation Challenges

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Semester Project , Internship , Bachelor Thesis , Master Thesis

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Published since: 2025-10-15 , Earliest start: 2024-07-01 , Latest end: 2025-06-30

Organization Functional Materials Laboratory

Hosts Gregorini Michele

Topics Information, Computing and Communication Sciences , Engineering and Technology

Smart Microcapsules for Biomedical Advances

This Master's thesis/semester project focuses on the microfluidic fabrication of microcapsules with multi-environmental responsiveness. The aim is to develop microcapsule-based microrobots capable of adapting to various environmental cues. We envision that these microrobots will be used for complex tasks in biomedical applications.

Keywords

Microfluidics, Microcapsules, Microrobotics, Responsive Polymers, Biomedical Engineering

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Semester Project , Internship , Master Thesis , Student Assistant / HiWi , ETH Zurich (ETHZ)

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Published since: 2025-10-14 , Earliest start: 2026-01-19

Organization Multiscale Robotics Lab

Hosts Hu Minghan

Topics Medical and Health Sciences , Engineering and Technology , Chemistry

Intelligent Micromachines Made from Droplet-Based Factory

We invite applications for a Master's thesis / semester project that focuses on the fabrication of microrobots with custom shapes. Using our developed droplet printing technique, this project will explore how different microrobot shapes, created by different magnetic fields and materials, influence their control behaviors in blood vessels. This research aims to advance biomedical technologies, particularly in targeted drug delivery and minimally invasive procedures.

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Microrobotics, 4D Printing, Soft Materials, Biomedical Devices

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Semester Project , Master Thesis , Student Assistant / HiWi , ETH Zurich (ETHZ)

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Published since: 2025-10-14 , Earliest start: 2026-02-02

Organization Multiscale Robotics Lab

Hosts Hu Minghan

Topics Engineering and Technology , Chemistry

Wireless Motion and Health Monitoring with Triboelectric Nanogenerators using a Custom Readout Circuit

This project aims to design and realize a custom single-PCB wireless readout circuit optimized for triboelectric nanogenerators (TENGs) for motion and health monitoring. Unlike previous designs that relied on assembling multiple commercial off-the-shelf PCBs, this project will integrate the functionalities of signal conditioning, energy harvesting, and wireless data transmission onto one compact, low-power circuit board). This PCB will be used to facilitate wireless joint angle analysis and fatigue monitoring during repetitive human movements using machine learning and deep learning.

Keywords

TENG, energy harvesting, wireless circuits, PCB design, low-power electronics, sensors, movement, mobile health, wearables

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Semester Project , Master Thesis

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Published since: 2025-10-14 , Earliest start: 2025-10-01 , Latest end: 2026-08-31

Organization Biomedical and Mobile Health Technology Lab

Hosts Otesteanu Corin, Dr

Topics Engineering and Technology

Machine learning for Motion Estimation and Fatigue Monitoring Using Triboelectric Nanogenerators

This project explores the feasibility of using triboelectric nanogenerators (TENGs) for joint angle analysis and fatigue monitoring during repetitive human movements using machine learning and deep learning.

Keywords

machine learning, artificial intelligence, generative AI, triboelectric nanogenerator, joint angle estimation, motion analysis, fatigue

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Semester Project , Internship , Master Thesis

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Published since: 2025-10-14 , Earliest start: 2025-09-01 , Latest end: 2026-08-01

Organization Biomedical and Mobile Health Technology Lab

Hosts Otesteanu Corin, Dr

Topics Medical and Health Sciences , Information, Computing and Communication Sciences , Engineering and Technology

Monitoring in-vitro neural network dynamics using microelectrode arrays

Join our interdisciplinary research team to explore the fascinating world of neuronal networks in vitro. These master projects focus on culturing neurons on CMOS-based microelectrode arrays (MEAs) to study their electrophysiological properties. The exact project scope will be tailored to your interests and background, offering a unique opportunity to contribute to cutting-edge neuroscience and bioengineering research.

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Neuroscience, Cell Culture, CMOS MEA, Electrophysiology, In Vitro Models, Neural Networks, Bioengineering, Neurotechnology

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Semester Project , Internship , Lab Practice , Master Thesis

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Published since: 2025-10-13 , Earliest start: 2025-06-15

Organization Bio Engineering Laboratory

Hosts Cardes Fernando

Topics Medical and Health Sciences , Engineering and Technology , Biology

Microelectronic circuit design for neural interfaces in 0.18um CMOS technology

This project is about the development of integrated circuits to study neurons and neural networks, and may comprise different parts of the design including analog and/or digital microelectronics, PCB design, signal processing and programming.

Keywords

Microelectronics, CMOS, circuit design, electronics, PCB, signal processing, neural interface.

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Semester Project , Internship , Bachelor Thesis , Master Thesis

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Published since: 2025-10-13 , Earliest start: 2022-01-03

Organization Bio Engineering Laboratory

Hosts Cardes Fernando

Topics Engineering and Technology

Learning-based object orientation prediction for handovers

Humans are exceptional at handovers. Besides timing and spatial precision, they also have a high-level understanding of how the other person wants to use the object that is handed over. This information is needed to hand over an object, such that it can be used directly for a specific task. While robots can reason about grasp affordances, the integration of this information with perception and control is missing.

Keywords

Robot-Human Handover, Human-Robot-Interaction, Mobile Manipulation, Robotics

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Semester Project , Master Thesis

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Published since: 2025-10-13 , Earliest start: 2025-02-01 , Latest end: 2025-12-31

Organization Robotic Systems Lab

Hosts Scheidemann Carmen , Tulbure Andreea

Topics Information, Computing and Communication Sciences , Engineering and Technology

Microfabrication and characterization of microelectrodes for neural interfaces

The focus of this project is on the fabrication of microelectrodes for advanced neural interfaces in a cutting-edge cleanroom environment. Our research aims to develop high-resolution neural probes utilizing state-of-the-art microfabrication techniques.

Keywords

Microfabrication; Cleanroom; Neural Interfaces; Microelectrode Arrays; Biomedical Devices; Nanotechnology; Electrochemical Deposition; Neurotechnology; Semiconductor Processing; Bioengineering.

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Published since: 2025-10-13 , Earliest start: 2023-12-01

Organization Bio Engineering Laboratory

Hosts Cardes Fernando

Topics Engineering and Technology

HandoverNarrate: Language-Guided Task-Aware Motion Planning for Handovers with Legged Manipulators

This project addresses the challenge of task-oriented human-robot handovers, where a robot must transfer objects in a manner that directly facilitates the human’s next action. In our prior work, we demonstrated that robots can present objects appropriately for immediate human use by leveraging large language models (LLMs) to reason about task context. However, integrating task-specific physical constraints—such as ensuring a full mug remains upright during transport—into the motion planning process remains unsolved. In this project, we aim to extend our existing motion planning framework for legged manipulators by incorporating such constraints. We propose using LLMs to dynamically generate task-aware constraint formulations based on high-level task descriptions and object states. These constraints will then be used to adjust the cost function of the model predictive controller in real time, enabling more context-sensitive and physically appropriate handovers.

Keywords

language-guided motion planning, legged robotics, human-robot collaboration

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Published since: 2025-10-13

Applications limited to ETH Zurich

Organization Robotic Systems Lab

Hosts Tulbure Andreea

Topics Information, Computing and Communication Sciences

Development of a High-Throughput Screening Platform Using Genome Editing, Human Neurons, and High-Density Microelectrode Array Recordings

Genetic screens have been used to probe how autism spectrum disorder (ASD)–associated mutations affect neurogenesis and differentiation. Yet, despite substantial effort, it remains difficult to disentangle cell-autonomous from network-level dysfunctions, and to relate their interplay to ASD’s diverse clinical phenotypes. This project aims to develop a multi-modal, high-throughput loss-of-function screening platform to study ASD-related mutations in human neurons. The methodology will enable perturbation screens and the analysis of how induced genetic alterations shape single-neuron and network-level electrophysiological features. To assess cell-type–specific perturbation effects in excitatory and inhibitory neurons, we will apply transcription-factor (TF)-based forward programming of human induced pluripotent stem cells (iPSCs) combined with combinatorial morphogen treatments. High-density microelectrode array (HD-MEA) recordings coupled to immunohistochemistry and single-cell gene expression analysis will provide an integrated view of how gene knock-outs influence neuronal development and function.

Keywords

Human induced pluripotent stem cells, CRISPR/Cas9 genome editing, neuronal networks, high-density microelectrode array electrophysiology

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Published since: 2025-10-10 , Earliest start: 2025-11-01 , Latest end: 2026-09-30

Organization Bio Engineering Laboratory

Hosts Schröter Manuel

Topics Medical and Health Sciences

Student internship - Engineering the Microstructure of Bacterial Cellulose for Sustainable Applications

Biological systems offer routes to build matter with controlled structure and function across scales. Among them, bacterial cellulose (BC) is uniquely attractive: produced as a fibrillar network with high purity and robust mechanical properties, it finds applications in diverse sectors including cosmetics, energy devices, and the biomedical industry. However, most research has targeted BC production yield and cost, while its microstructure, specifically fiber alignment, remains poorly understood and largely engineered post-production.

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Sustainability - Hydrogel - Mechanical testing - Microscopy

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Semester Project , Internship , Bachelor Thesis , Master Thesis , Master Project (D-MATL)

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Published since: 2025-10-07 , Earliest start: 2026-02-16 , Latest end: 2026-07-01

Organization Complex Materials

Hosts Ansart Elise

Topics Engineering and Technology

How Mechanical Forces Shape Cell Fate – and the Future of Regenerative Medicine

Project Summary We’re developing a powerful new in vitro model to untangle the complex mechanical cues—osmotic pressure and substrate stiffness—that skin cells experience every day. These signals are deeply intertwined in the body, but we’re building a system to decouple and precisely control them, for the first time. Why? Because understanding how cells respond to these forces is crucial for engineering functional tissues, guiding organ regeneration, and tackling mechanobiology-driven diseases like fibrosis.

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Key words: mechanical stresses, cell behavior, fibroblasts, immunostaining.

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Master Thesis

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Published since: 2025-10-07 , Earliest start: 2026-02-01 , Latest end: 2026-10-01

Organization Macromolecular Engineering Laboratory

Hosts Cuni Filippo

Topics Medical and Health Sciences , Engineering and Technology , Biology

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